Police say a man fled with thousands of pounds after struggling with the driver of a cash van outside Sainsbury's supermarket in Bitterne.
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Police were called to Bitterne precinct on Wednesday Tuesday morning (Dec 29) after the driver was approached by an offender who demanded a box containing the cash.
He then fled in a blue BMW, which was later recovered.
The driver of the van wasn't injured.
Police want to hear from anyone who saw the robbery or the car: call DC Jonathan Matthews at Southampton CID on 101, quoting 44150456459, or call the Crimestoppers charity anonymously on 0800 555 111.